Milan to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Napoli Centrale and arrive at Castelvetrano every about 12 hours on average. If travelling with Trenitalia, you need to know the Milan to Castelvetrano train schedule: the first train leaves at 23:53, while the last ride is at 23:53. A Milan to Castelvetrano train cost about 83.5 €. But how long is the train ride from Milan to Castelvetrano? Your journey takes about 13 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Milan to Castelvetrano and find low cost tickets starting from 189 €!