Monopoli to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Monopoli and arrive at Ancona every 60 minutes on average. If travelling with Trenitalia, you need to know the Monopoli to Ancona train schedule: the first train leaves at 06:23, while the last ride is at 23:27. A Monopoli to Ancona train cost about 41.1 €. But how long is the train ride from Monopoli to Ancona? Your journey takes about 5 hours on average. Trenitalia offers 2 direct trains between these two cities.