Naples to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Napoli Centrale and arrive at Alessandria every 60 minutes on average. If travelling with Trenitalia, you need to know the Naples to Alessandria train schedule: the first train leaves at 04:04, while the last ride is at 22:07. A Naples to Alessandria train cost about 39.90 €. But how long is the train ride from Naples to Alessandria? Your journey takes about 8 hours on average. Trenitalia offers 1 direct trains between these two cities. Thanks to Trenitalia, offers, you can save on your trip from Naples to Alessandria and find low cost tickets starting from 29 €! If you need to travel this week, prices range from 56.60 € to 72.53€.