Novi Ligure to Busto Arsizio trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Novi Ligure and arrive at Busto Arsizio every 60 minutes on average. If travelling with Trenitalia, you need to know the Novi Ligure to Busto Arsizio train schedule: the first train leaves at 04:10, while the last ride is at 20:44. A Novi Ligure to Busto Arsizio train cost about 11.8 €. But how long is the train ride from Novi Ligure to Busto Arsizio? Your journey takes about 4 hours on average.