Novi Ligure to Mazara del Vallo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Novi Ligure and arrive at Mazara del Vallo every about 4 hours on average. If travelling with Trenitalia, you need to know the Novi Ligure to Mazara del Vallo train schedule: the first train leaves at 14:14, while the last ride is at 20:44. A Novi Ligure to Mazara del Vallo train cost about 98.7 €. But how long is the train ride from Novi Ligure to Mazara del Vallo? Your journey takes about 12 hours on average.