Osimo to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Osimo-Castelfidardo and arrive at Avola every about 4 hours on average. If travelling with Trenitalia, you need to know the Osimo to Avola train schedule: the first train leaves at 14:49, while the last ride is at 15:48. A Osimo to Avola train cost about 103.35 €. But how long is the train ride from Osimo to Avola? Your journey takes about 19 hours on average.