Osimo to Messina trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 7 daily rides to get from Osimo to Messina. Trains leave from Osimo-Castelfidardo,Salerno and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Osimo to Messina train schedule: the first train leaves at 06:44, while the last ride is at 22:01. A Osimo to Messina train cost about 69.75 €. But how long is the train ride from Osimo to Messina? Your journey takes about 13 hours on average. If you need to travel this week, prices range from 45.50 € to 45.50€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Osimo to Messina with fares starting from 12.90€, saving 71% on average.