Padua to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Padova and arrive at Comiso every about 3 hours on average. If travelling with Trenitalia, you need to know the Padua to Comiso train schedule: the first train leaves at 15:32, while the last ride is at 18:53. A Padua to Comiso train cost about 108.65 €. But how long is the train ride from Padua to Comiso? Your journey takes about 17 hours on average.