Pagani to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pagani and arrive at Messina Centrale every about 4 hours on average. If travelling with Trenitalia, you need to know the Pagani to Messina train schedule: the first train leaves at 08:21, while the last ride is at 21:46. A Pagani to Messina train cost about 20.8 €. But how long is the train ride from Pagani to Messina? Your journey takes about 7 hours on average.