Perugia to Castelvetrano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Perugia and arrive at Castelvetrano every about 12 hours on average. If travelling with Trenitalia, you need to know the Perugia to Castelvetrano train schedule: the first train leaves at 17:56, while the last ride is at 17:56. A Perugia to Castelvetrano train cost about 116.65 €. But how long is the train ride from Perugia to Castelvetrano? Your journey takes about 19 hours on average.