Pisa to Alpignano trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Alpignano every 60 minutes on average. If travelling with Trenitalia, you need to know the Pisa to Alpignano train schedule: the first train leaves at 03:26, while the last ride is at 16:29. A Pisa to Alpignano train cost about 31.75 €. But how long is the train ride from Pisa to Alpignano? Your journey takes about 5 hours on average.