Pisa to Ancona trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Ancona every 60 minutes on average. If travelling with Trenitalia, you need to know the Pisa to Ancona train schedule: the first train leaves at 04:15, while the last ride is at 19:54. A Pisa to Ancona train cost about 42.0 €. But how long is the train ride from Pisa to Ancona? Your journey takes about 5 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pisa to Ancona and find low cost tickets starting from 29 €!