Pisa to Avola trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Avola every about 2 hours on average. If travelling with Trenitalia, you need to know the Pisa to Avola train schedule: the first train leaves at 07:32, while the last ride is at 19:45. A Pisa to Avola train cost about 100.6 €. But how long is the train ride from Pisa to Avola? Your journey takes about 16 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pisa to Avola and find low cost tickets starting from 48 €!