Pisa to Catania trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Catania Acquicella every about 12 hours on average. If travelling with Trenitalia, you need to know the Pisa to Catania train schedule: the first train leaves at 19:13, while the last ride is at 19:13. A Pisa to Catania train cost about 214.5 €. But how long is the train ride from Pisa to Catania? Your journey takes about 18 hours on average.