Pisa to Enna trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Enna every about 4 hours on average. If travelling with Trenitalia, you need to know the Pisa to Enna train schedule: the first train leaves at 00:01, while the last ride is at 19:13. A Pisa to Enna train cost about 75.35 €. But how long is the train ride from Pisa to Enna? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pisa to Enna and find low cost tickets starting from 51 €!