Pisa to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Noto every about 2 hours on average. If travelling with Trenitalia, you need to know the Pisa to Noto train schedule: the first train leaves at 07:32, while the last ride is at 19:45. A Pisa to Noto train cost about 101.2 €. But how long is the train ride from Pisa to Noto? Your journey takes about 16 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pisa to Noto and find low cost tickets starting from 113 €!