Pisa to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pisa Centrale and arrive at Varese every about 2 hours on average. If travelling with Trenitalia, you need to know the Pisa to Varese train schedule: the first train leaves at 03:26, while the last ride is at 19:09. A Pisa to Varese train cost about 25.9 €. But how long is the train ride from Pisa to Varese? Your journey takes about 7 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Pisa to Varese and find low cost tickets starting from 19 €!