Pistoia to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pistoia and arrive at Niscemi every about 2 hours on average. If travelling with Trenitalia, you need to know the Pistoia to Niscemi train schedule: the first train leaves at 09:12, while the last ride is at 21:44. A Pistoia to Niscemi train cost about 97.2 €. But how long is the train ride from Pistoia to Niscemi? Your journey takes about 14 hours on average.