Poggibonsi to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Poggibonsi-S. Gimignano and arrive at Niscemi every about 12 hours on average. If travelling with Trenitalia, you need to know the Poggibonsi to Niscemi train schedule: the first train leaves at 18:46, while the last ride is at 18:46. A Poggibonsi to Niscemi train cost about 233.25 €. But how long is the train ride from Poggibonsi to Niscemi? Your journey takes about 22 hours on average.