Pompei to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pompei and arrive at Palermo Notarbartolo every about 6 hours on average. If travelling with Trenitalia, you need to know the Pompei to Palermo train schedule: the first train leaves at 09:31, while the last ride is at 21:54. A Pompei to Palermo train cost about 59.8 €. But how long is the train ride from Pompei to Palermo? Your journey takes about 11 hours on average.