Pozzuoli to Brindisi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Pozzuoli Solfatara and arrive at Brindisi every about 2 hours on average. If travelling with Trenitalia, you need to know the Pozzuoli to Brindisi train schedule: the first train leaves at 07:23, while the last ride is at 07:23. A Pozzuoli to Brindisi train cost about 50.1 €. But how long is the train ride from Pozzuoli to Brindisi? Your journey takes about 6 hours on average.