Prato to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Prato Porta al Serraglio and arrive at Messina Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Prato to Messina train schedule: the first train leaves at 09:23, while the last ride is at 21:23. A Prato to Messina train cost about 82.15 €. But how long is the train ride from Prato to Messina? Your journey takes about 14 hours on average.