Prato to Palermo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 7 daily rides to get from Prato to Palermo. Trains leave from Prato Porta al Serraglio and arrive at Palermo Notarbartolo every about 2 hours on average. If travelling with Trenitalia, you need to know the Prato to Palermo train schedule: the first train leaves at 16:23, while the last ride is at 21:23. A Prato to Palermo train cost about 96.3 €. But how long is the train ride from Prato to Palermo? Your journey takes about 18 hours on average.