Quattromiglia to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Castiglione Cosentino and arrive at Comiso every about 12 hours on average. If travelling with Trenitalia, you need to know the Quattromiglia to Comiso train schedule: the first train leaves at 11:27, while the last ride is at 11:27. A Quattromiglia to Comiso train cost about 43.35 €. But how long is the train ride from Quattromiglia to Comiso? Your journey takes about 12 hours on average.