Rome to Agrigento trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 3 daily rides to get from Rome to Agrigento. Trains leave from Roma Termini and arrive at Agrigento Bassa every about 4 hours on average. The trip by train from Rome to Agrigento last on average 13:20 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with Trenitalia, you need to know the Rome to Agrigento train schedule: the first train leaves at 07:35, while the last ride is at 22:26. A Rome to Agrigento train cost about 70.0 €. But how long is the train ride from Rome to Agrigento? Your journey takes about 15 hours on average.