Rome to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Roma Termini and arrive at Varese every 60 minutes on average. If travelling with Trenitalia, you need to know the Rome to Varese train schedule: the first train leaves at 06:00, while the last ride is at 23:00. A Rome to Varese train cost about 61.3 €. But how long is the train ride from Rome to Varese? Your journey takes about 5 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Rome to Varese and find low cost tickets starting from 44 €!