San Miniato to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from S. Romano-Montopoli-S. Croce and arrive at Niscemi every about 6 hours on average. If travelling with Trenitalia, you need to know the San Miniato to Niscemi train schedule: the first train leaves at 01:28, while the last ride is at 19:18. A San Miniato to Niscemi train cost about 172.05 €. But how long is the train ride from San Miniato to Niscemi? Your journey takes about 21 hours on average.