Sant'Anastasia to Venice trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Casalnuovo di Napoli, Napoli Centrale and arrive at Venezia S. Lucia every about 2 hours on average. If travelling with Trenitalia, you need to know the Sant'Anastasia to Venice train schedule: the first train leaves at 09:20, while the last ride is at 14:56. A Sant'Anastasia to Venice train cost about 99.0 €. But how long is the train ride from Sant'Anastasia to Venice? Your journey takes about 6 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sant'Anastasia to Venice and find low cost tickets starting from 22 €!