Santeramo in Colle to Palermo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Santeramo and arrive at Palermo Notarbartolo every about 12 hours on average. If travelling with Trenitalia, you need to know the Santeramo in Colle to Palermo train schedule: the first train leaves at 22:57, while the last ride is at 22:57. A Santeramo in Colle to Palermo train cost about 62.8 €. But how long is the train ride from Santeramo in Colle to Palermo? Your journey takes about 20 hours on average.