Santeramo in Colle to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Santeramo and arrive at Trieste Centrale every about 2 hours on average. If travelling with Trenitalia, you need to know the Santeramo in Colle to Trieste train schedule: the first train leaves at 07:33, while the last ride is at 07:33. A Santeramo in Colle to Trieste train cost about 159.05 €. But how long is the train ride from Santeramo in Colle to Trieste? Your journey takes about 12 hours on average.