Segrate to Caltagirone trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Segrate and arrive at Caltagirone every about 6 hours on average. If travelling with Trenitalia, you need to know the Segrate to Caltagirone train schedule: the first train leaves at 17:59, while the last ride is at 19:29. A Segrate to Caltagirone train cost about 112.4 €. But how long is the train ride from Segrate to Caltagirone? Your journey takes about 12 hours on average.