Senago to Syracuse trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Rho-Fiera Milano and arrive at Siracusa every about 2 hours on average. If travelling with Trenitalia, you need to know the Senago to Syracuse train schedule: the first train leaves at 06:18, while the last ride is at 21:31. A Senago to Syracuse train cost about 124.8 €. But how long is the train ride from Senago to Syracuse? Your journey takes about 18 hours on average.