Senigallia to Alessandria trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Senigallia and arrive at Alessandria every about 1 hour on average. If travelling with Trenitalia, you need to know the Senigallia to Alessandria train schedule: the first train leaves at 04:57, while the last ride is at 19:02. A Senigallia to Alessandria train cost about 28.95 €. But how long is the train ride from Senigallia to Alessandria? Your journey takes about 6 hours on average.