Seregno to Agrigento trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Seregno and arrive at Agrigento Centrale every about 3 hours on average. If travelling with Trenitalia, you need to know the Seregno to Agrigento train schedule: the first train leaves at 17:30, while the last ride is at 19:30. A Seregno to Agrigento train cost about 79.8 €. But how long is the train ride from Seregno to Agrigento? Your journey takes about 22 hours on average.