Seregno to Noto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Seregno and arrive at Noto every about 4 hours on average. If travelling with Trenitalia, you need to know the Seregno to Noto train schedule: the first train leaves at 17:30, while the last ride is at 19:30. A Seregno to Noto train cost about 88.25 €. But how long is the train ride from Seregno to Noto? Your journey takes about 19 hours on average.