Sesto San Giovanni to Vasto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Sesto S. Giovanni and arrive at Porto di Vasto every about 2 hours on average. If travelling with Trenitalia, you need to know the Sesto San Giovanni to Vasto train schedule: the first train leaves at 06:29, while the last ride is at 06:29. A Sesto San Giovanni to Vasto train cost about 142.8 €. But how long is the train ride from Sesto San Giovanni to Vasto? Your journey takes about 7 hours on average.