Sienna to Ancona trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 12 daily rides to get from Sienna to Ancona. Trains leave from Siena and arrive at Ancona every 60 minutes on average. If travelling with Trenitalia, you need to know the Sienna to Ancona train schedule: the first train leaves at 06:00, while the last ride is at 18:47. A Sienna to Ancona train cost about 29.65 €. But how long is the train ride from Sienna to Ancona? Your journey takes about 6 hours on average.