Sienna to Vasto trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Siena and arrive at Porto di Vasto every 60 minutes on average. If travelling with Trenitalia, you need to know the Sienna to Vasto train schedule: the first train leaves at 06:36, while the last ride is at 20:18. A Sienna to Vasto train cost about 31.85 €. But how long is the train ride from Sienna to Vasto? Your journey takes about 9 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Sienna to Vasto and find low cost tickets starting from 59 €!