To get from Sienna a Vimodrone by train you can catch one of the 65 trains that everyday travel between Siena and Segrate, the closest station to the city. For your trip from Siena to Segrate by train you can choose to leave from one of Siena main stations: Siena, Firenze S. M. Novella The trip by train from Siena to Segrate last on average 01:40 travelling with high-speed trains (Frecciarossa or Italotreno) If travelling with ItaloTreno, you need to know the Siena to Segrate train schedule: the first train leaves at 08:25, while the last ride is at 21:25. ItaloTreno offers 12 direct trains between these two cities. There are also Trenitalia trains from Siena to Segrate; you can compare ItaloTreno and Trenitalia with Wanderio, so that you find the best fare in a quick and simple way. A Siena to Segrate train ticket with Trenitalia cost 24.90 € on average and you can find rides from 06:25 to 22:00. If you need to travel this week, prices range from 34.90 € to 54.90€. Booking your train ticket a few weeks in advance though, you can find low cost trains from Siena to Segrate with fares starting from 12.90€, saving 69% on average.