To get from Spoleto a Casarano by train you can catch one of the 10 trains that everyday travel between Spoleto and Lecce, the closest station to the city. For your trip from Spoleto to Lecce by train you can choose to leave from one of Spoleto main stations: Spoleto If travelling with Trenitalia, you need to know the Spoleto to Lecce train schedule: the first train leaves at 07:16, while the last ride is at 22:26. A Spoleto to Lecce train cost about 57.6 €. But how long is the train ride from Spoleto to Lecce? Your journey takes about 9 hours on average.