Spoleto to Milazzo trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 5 daily rides to get from Spoleto to Milazzo. If travelling with Trenitalia, you need to know the Spoleto to Milazzo train schedule: the first train leaves at 05:15, while the last ride is at 19:00. A Spoleto to Milazzo train cost about 72.0 €. But how long is the train ride from Spoleto to Milazzo? Your journey takes about 11 hours on average.