Spoleto to Trieste trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Spoleto and arrive at Trieste Centrale every about 1 hour on average. If travelling with Trenitalia, you need to know the Spoleto to Trieste train schedule: the first train leaves at 12:06, while the last ride is at 20:48. A Spoleto to Trieste train cost about 54.2 €. But how long is the train ride from Spoleto to Trieste? Your journey takes about 10 hours on average.