Spoleto to Varese trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Spoleto and arrive at Varese every about 3 hours on average. If travelling with Trenitalia, you need to know the Spoleto to Varese train schedule: the first train leaves at 12:06, while the last ride is at 22:26. A Spoleto to Varese train cost about 59.4 €. But how long is the train ride from Spoleto to Varese? Your journey takes about 10 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Spoleto to Varese and find low cost tickets starting from 23 €!