Spoleto to Vicenza trains might be a good value for money solution; travelling in Italy by train is often rather cheap and faster than taking a bus indeed. You can count on 26 daily rides to get from Spoleto to Vicenza. Trains leave from Spoleto and arrive at Vicenza every 30 minutes on average. If travelling with Trenitalia, you need to know the Spoleto to Vicenza train schedule: the first train leaves at 06:15, while the last ride is at 22:26. A Spoleto to Vicenza train cost about 31.75 €. But how long is the train ride from Spoleto to Vicenza? Your journey takes about 7 hours on average.