Spoleto to Vicenza trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Spoleto and arrive at Vicenza every 30 minutes on average. If travelling with Trenitalia, you need to know the Spoleto to Vicenza train schedule: the first train leaves at 06:15, while the last ride is at 22:26. A Spoleto to Vicenza train cost about 31.75 €. But how long is the train ride from Spoleto to Vicenza? Your journey takes about 7 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Spoleto to Vicenza and find low cost tickets starting from 18 €!