To get from Syracuse a Casa Santa by train you can catch one of the 1 trains that everyday travel between Siracusa and Trapani, the closest station to the city. For your trip from Siracusa to Trapani by train you can choose to leave from one of Siracusa main stations: Siracusa If travelling with Trenitalia, you need to know the Siracusa to Trapani train schedule: the first train leaves at 07:20, while the last ride is at 07:20. A Siracusa to Trapani train cost about 29.1 €. But how long is the train ride from Siracusa to Trapani? Your journey takes about 11 hours on average.