Tolentino to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Tolentino and arrive at Niscemi every about 2 hours on average. If travelling with Trenitalia, you need to know the Tolentino to Niscemi train schedule: the first train leaves at 06:45, while the last ride is at 20:52. A Tolentino to Niscemi train cost about 89.25 €. But how long is the train ride from Tolentino to Niscemi? Your journey takes about 1 hour on average.