Tortona to Comiso trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Tortona and arrive at Comiso every about 2 hours on average. If travelling with Trenitalia, you need to know the Tortona to Comiso train schedule: the first train leaves at 09:08, while the last ride is at 21:27. A Tortona to Comiso train cost about 118.9 €. But how long is the train ride from Tortona to Comiso? Your journey takes about 12 hours on average.