Venice to Niscemi trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Venezia S. Lucia and arrive at Niscemi every about 4 hours on average. If travelling with Trenitalia, you need to know the Venice to Niscemi train schedule: the first train leaves at 00:08, while the last ride is at 00:08. A Venice to Niscemi train cost about 142.65 €. But how long is the train ride from Venice to Niscemi? Your journey takes about 21 hours on average.