Agrigento to Messina trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Agrigento Centrale and arrive at Messina Centrale every about 1 hour on average. If travelling with Trenitalia, you need to know the Agrigento to Messina train schedule: the first train leaves at 06:14, while the last ride is at 18:14. A Agrigento to Messina train cost about 13.9 €. But how long is the train ride from Agrigento to Messina? Your journey takes about 5 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Agrigento to Messina and find low cost tickets starting from 15 €!