Alessandria to Milazzo trains might be a good value for money solution: travelling in Italy by train is often rather cheap and faster than taking a bus indeed Trains leave from Alessandria and arrive at Milazzo every about 2 hours on average. If travelling with Trenitalia, you need to know the Alessandria to Milazzo train schedule: the first train leaves at 13:31, while the last ride is at 22:59. A Alessandria to Milazzo train cost about 111.5 €. But how long is the train ride from Alessandria to Milazzo? Your journey takes about 17 hours on average. Thanks to Trenitalia, offers, you can save on your trip from Alessandria to Milazzo and find low cost tickets starting from 52 €!